Recombinant Human IL-4
- 型號： 200-04-10
- 更新時間： 2024-05-24
- 上一個：200-04-2Recombinant Human IL-4
- 下一個：213-13-10Recombinant Murine IL-3
Recombinant Human IL-4：
Synonyms : BCGF, BCDF, B cell stimulating factor （BSF-1） Description : IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
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