BD Gentest微粒體/HLM Pooled,現(xiàn)貨
訂貨:; :鐘() : BD貨號(hào):452161 HLM Pooled Donors 20 mg/mL 人肝微粒體 美國(guó)BD 微粒體產(chǎn)品描述 肝微粒體 是來(lái)源于肝臟內(nèi)質(zhì)網(wǎng)膜的亞細(xì)胞組分,富含大量的藥物代謝酶,被廣泛的用來(lái)評(píng)價(jià)藥物或候選化合物的體外代謝特征:(A)、代謝穩(wěn)定性(體外T1/2 和固有清除率CLint);(B)CYP450代謝表型研究(確認(rèn)主要的代謝酶);(C)藥物對(duì)CYP450各亞型酶的抑制作用(IC50);(D)代謝物和代謝途徑的鑒定。 一.BD公司可以提供: · 各種種屬的肝微粒體(包括人、大鼠和小鼠) · 單個(gè)個(gè)體產(chǎn)品和混合產(chǎn)品 · 雌性和雄性產(chǎn)品 · 誘導(dǎo)和非誘導(dǎo)產(chǎn)品(大鼠和小鼠) 二.規(guī)格:凍存管包裝,20mg/ml,0.5ml/管。 大量現(xiàn)貨!!! BD 452161 HLM Pooled Donors20mg/ml 0.5ml 944 Pooled mixture of liver microsomes from different individual donors. Pathogenicity testing of each liver has been performed using a PCR protocol. Each liver was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C. Immunoquantitation (pmol/mg) of the following proteins is reported on the product insert: CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A.Description
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